Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.S551P

c.1651T>C

Surrounding Variants

1 paper

NM_000840.3

p.Q553K

c.1657C>A

1 paper

NM_000840.3

p.D548N

c.1642G>A

1 paper

NM_000840.3

p.M547K

c.1640T>A

1 paper

NM_000840.3

p.M547V

c.1639A>G

1 paper

NM_000840.3

p.C546F

c.1637G>T

1 paper

NM_000840.3

p.A541D

c.1622C>A

1 paper

NM_000840.3

p.A541V

c.1622C>T

3 papers

NM_000840.3

p.G561E

c.1682G>A

2 papers

NM_000840.3

p.C562C

c.1686C>T

4 papers

NM_000840.3

p.E538K

c.1612G>A

1 paper

NM_000840.3

p.L565H

c.1694T>A

1 paper

NM_000840.3

p.E535K

c.1603G>A