Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.L565H

c.1694T>A

Surrounding Variants

2 papers

NM_000840.3

p.C562C

c.1686C>T

3 papers

NM_000840.3

p.G561E

c.1682G>A

1 paper

NM_000840.3

p.W572*

c.1715G>A

1 paper

NM_000840.3

p.W572*

c.1716G>A

1 paper

NM_000840.3

p.E573K

c.1717G>A

1 paper

NM_000840.3

p.D574D

c.1722C>T

3 papers

NM_000840.3

p.A575T

c.1723G>A

1 paper

NM_000840.3

p.Q553K

c.1657C>A

2 papers

NM_000840.3

p.I578N

c.1733T>A

1 paper

NM_000840.3

p.G579G

c.1737C>A

1 paper

NM_000840.3

p.S551P

c.1651T>C

1 paper

NM_000840.3

p.D548N

c.1642G>A