Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.M593I

c.1779G>C

Surrounding Variants

1 paper

NM_000840.3

p.M593I

c.1779G>A

1 paper

NM_000840.3

p.M593I

c.1779G>T

1 paper

NM_000840.3

p.M593T

c.1778T>C

1 paper

NM_000840.3

p.V595delFs

c.1783delG

1 paper

NM_000840.3

p.V595I

c.1783G>A

1 paper

NM_000840.3

p.T596I

c.1787C>T

1 paper

NM_000840.3

p.F588ins2

c.1762_1763ins6

1 paper

NM_000840.3

p.L586M

c.1756C>A

1 paper

NM_000840.3

p.N602S

c.1805A>G

1 paper

NM_000840.3

p.C585insFs

c.1753_1754insCA

1 paper

NM_000840.3

p.C585fs

c.1753_1754fs

1 paper

NM_000840.3

p.A584A

c.1752C>T