Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.T604delFs

c.1810delA

Surrounding Variants

1 paper

NM_000840.3

p.T604fs

c.1810_1811fs

1 paper

NM_000840.3

p.N602S

c.1805A>G

1 paper

NM_000840.3

p.P605A

c.1813C>G

1 paper

NM_000840.3

p.P605S

c.1813C>T

1 paper

NM_000840.3

p.A609V

c.1826C>T

6 papers

NM_000840.3

p.S610L

c.1829C>T

1 paper

NM_000840.3

p.T596I

c.1787C>T

1 paper

NM_000840.3

p.R612*

c.1834C>T

1 paper

NM_000840.3

p.V595I

c.1783G>A

1 paper

NM_000840.3

p.V595delFs

c.1783delG

1 paper

NM_000840.3

p.M593I

c.1779G>A

1 paper

NM_000840.3

p.M593I

c.1779G>C