Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.I696N

c.2087T>A

Surrounding Variants

1 paper

NM_000840.3

p.G694A

c.2081G>C

1 paper

NM_000840.3

p.G694C

c.2080G>T

1 paper

NM_000840.3

p.I691V

c.2071A>G

1 paper

NM_000840.3

p.V689F

c.2065G>T

1 paper

NM_000840.3

p.S704C

c.2111C>G

1 paper

NM_000840.3

p.S704F

c.2111C>T

1 paper

NM_000840.3

p.S686R

c.2058T>A

1 paper

NM_000840.3

p.S686R

c.2058T>G

1 paper

NM_000840.3

p.S686R

c.2056A>C

1 paper

NM_000840.3

p.P685A

c.2053C>G

1 paper

NM_000840.3

p.I683S

c.2048T>G

1 paper

NM_000840.3

p.P712L

c.2135C>T