Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_000840.3

p.E724K

c.2170G>A

Surrounding Variants

2 papers

NM_000840.3

p.E724G

c.2171A>G

1 paper

NM_000840.3

p.T725A

c.2173A>G

1 paper

NM_000840.3

p.R723W

c.2167C>T

2 papers

NM_000840.3

p.T718I

c.2153C>T

1 paper

NM_000840.3

p.Y717C

c.2150A>G

1 paper

NM_000840.3

p.R716M

c.2147G>T

1 paper

NM_000840.3

p.G713G

c.2139C>A

1 paper

NM_000840.3

p.G713G

c.2139C>T

1 paper

NM_000840.3

p.S735C

c.2204C>G

1 paper

NM_000840.3

p.P712L

c.2135C>T

1 paper

NM_000840.3

p.Y743C

c.2228A>G

1 paper

NM_000840.3

p.S704C

c.2111C>G