Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.V745L

c.2233G>T

Surrounding Variants

1 paper

NM_000840.3

p.V745L

c.2233G>C

4 papers

NM_000840.3

p.D744N

c.2230G>A

1 paper

NM_000840.3

p.Y743C

c.2228A>G

1 paper

NM_000840.3

p.S735C

c.2204C>G

2 papers

NM_000840.3

p.A755T

c.2263G>A

1 paper

NM_000840.3

p.T758K

c.2273C>A

2 papers

NM_000840.3

p.T758M

c.2273C>T

2 papers

NM_000840.3

p.R759Q

c.2276G>A

1 paper

NM_000840.3

p.P762T

c.2284C>A

1 paper

NM_000840.3

p.P762A

c.2284C>G

1 paper

NM_000840.3

p.E763A

c.2288A>C

1 paper

NM_000840.3

p.T725A

c.2173A>G