Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.G772S

c.2314G>A

Surrounding Variants

1 paper

NM_000840.3

p.G772D

c.2315G>A

1 paper

NM_000840.3

p.Y776H

c.2326T>C

5 papers

NM_000840.3

p.E767K

c.2299G>A

1 paper

NM_000840.3

p.T778M

c.2333C>T

1 paper

NM_000840.3

p.F765S

c.2294T>C

1 paper

NM_000840.3

p.E763A

c.2288A>C

1 paper

NM_000840.3

p.P762T

c.2284C>A

1 paper

NM_000840.3

p.P762A

c.2284C>G

2 papers

NM_000840.3

p.R759Q

c.2276G>A

1 paper

NM_000840.3

p.T758K

c.2273C>A

2 papers

NM_000840.3

p.T758M

c.2273C>T

2 papers

NM_000840.3

p.A755T

c.2263G>A