Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.Y796C

c.2387A>G

Surrounding Variants

1 paper

NM_000840.3

p.D795G

c.2384A>G

1 paper

NM_000840.3

p.R797T

c.2390G>C

1 paper

NM_000840.3

p.Y790*

c.2370T>G

1 paper

NM_000840.3

p.F789_Y790insFs

c.2367_2368insA

1 paper

NM_000840.3

p.F789fs

c.2365_2366fs

1 paper

NM_000840.3

p.T778M

c.2333C>T

1 paper

NM_000840.3

p.Y776H

c.2326T>C

1 paper

NM_000840.3

p.G772D

c.2315G>A

1 paper

NM_000840.3

p.G772S

c.2314G>A

5 papers

NM_000840.3

p.E767K

c.2299G>A

1 paper

NM_000840.3

p.F765S

c.2294T>C

1 paper

NM_000840.3

p.E763A

c.2288A>C