Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.N833S

c.2498A>G

Surrounding Variants

1 paper

NM_000840.3

p.V835A

c.2504T>C

2 papers

NM_000840.3

p.T836A

c.2506A>G

1 paper

NM_000840.3

p.H837Q

c.2511C>A

1 paper

NM_000840.3

p.H837Q

c.2511C>G

1 paper

NM_000840.3

p.L827P

c.2480T>C

1 paper

NM_000840.3

p.L827M

c.2479C>A

1 paper

NM_000840.3

p.V823F

c.2467G>T

1 paper

NM_000840.3

p.V846A

c.2537T>C

1 paper

NM_000840.3

p.S847R

c.2539A>C

1 paper

NM_000840.3

p.S847N

c.2540G>A

1 paper

NM_000840.3

p.S847R

c.2541T>A

1 paper

NM_000840.3

p.S847R

c.2541T>G