Varaico: Literature-Extracted Genetic Variants

GRM4

139 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 77–483UCSCReceptor family ligand binding region

NCD3Gaa 468–519UCSCNine Cysteines Domain of family 3 GPCR

NCD3Gaa 515–566UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 534–794UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 4

HGNC Alias Symbols

GPRC1D; mGlu4; MGLUR4

Papers

RefSeq ID

Protein change

DNA change

1–12 of 164 variants

3 papers

NM_000841.4

p.D485D

c.1455T>C

3 papers

NM_000841.4

p.S486F

c.1457C>T

3 papers

NM_000841.4

p.F781S

c.2342T>C

2 papers

NM_000841.4

p.G53D

c.158G>A

2 papers

NM_000841.4

p.Q124R

c.371A>G

2 papers

NM_000841.4

p.S311A

c.931T>G

2 papers

NM_000841.4

p.W495*

c.1484G>A

2 papers

NM_000841.4

p.W495*

c.1485G>A

2 papers

NM_000841.4

p.T734T

c.2202A>G

2 papers

NM_000841.4

p.V797I

c.2389G>A

1 paper

NM_000841.4

p.K4N

c.12G>C

1 paper

NM_000841.4

p.G6D

c.17G>A