Varaico: Literature-Extracted Genetic Variants

GRM4

139 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 77–483UCSCReceptor family ligand binding region

NCD3Gaa 468–519UCSCNine Cysteines Domain of family 3 GPCR

NCD3Gaa 515–566UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 534–794UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 4

HGNC Alias Symbols

GPRC1D; mGlu4; MGLUR4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000841.4

p.T780A

c.2338A>G

Surrounding Variants

3 papers

NM_000841.4

p.F781S

c.2342T>C

1 paper

NM_000841.4

p.N782I

c.2345A>T

1 paper

NM_000841.4

p.E783Q

c.2347G>C

2 papers

NM_000841.4

p.V797I

c.2389G>A

1 paper

NM_000841.4

p.M761I

c.2283G>T

1 paper

NM_000841.4

p.M761I

c.2283G>C

1 paper

NM_000841.4

p.M761I

c.2283G>A

1 paper

NM_000841.4

p.L757L

c.2269C>T

1 paper

NM_000841.4

p.L757V

c.2269C>G

1 paper

NM_000841.4

p.S809L

c.2426C>T

1 paper

NM_000841.4

p.S749A

c.2245T>G

1 paper

NM_000841.4

p.S749T

c.2245T>A