Varaico: Literature-Extracted Genetic Variants

GRM4

139 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 77–483UCSCReceptor family ligand binding region

NCD3Gaa 468–519UCSCNine Cysteines Domain of family 3 GPCR

NCD3Gaa 515–566UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 534–794UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 4

HGNC Alias Symbols

GPRC1D; mGlu4; MGLUR4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000841.4

p.M663I

c.1989G>A

Surrounding Variants

1 paper

NM_000841.4

p.M663I

c.1989G>T

1 paper

NM_000841.4

p.M663I

c.1989G>C

1 paper

NM_000841.4

p.G660R

c.1978G>A

1 paper

NM_000841.4

p.A669T

c.2005G>A

1 paper

NM_000841.4

p.L670delFs

c.2010delC

1 paper

NM_000841.4

p.R679C

c.2035C>T

1 paper

NM_000841.4

p.V688A

c.2063T>C

1 paper

NM_000841.4

p.A697T

c.2089G>A

1 paper

NM_000841.4

p.V628L

c.1882G>T

1 paper

NM_000841.4

p.V628L

c.1882G>C

1 paper

NM_000841.4

p.A701T

c.2101G>A

1 paper

NM_000841.4

p.T602M

c.1805C>T