Varaico: Literature-Extracted Genetic Variants

GRM4

139 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 77–483UCSCReceptor family ligand binding region

NCD3Gaa 468–519UCSCNine Cysteines Domain of family 3 GPCR

NCD3Gaa 515–566UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 534–794UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 4

HGNC Alias Symbols

GPRC1D; mGlu4; MGLUR4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000841.4

p.D563A

c.1688A>C

Surrounding Variants

1 paper

NM_000841.4

p.T567A

c.1699A>G

1 paper

NM_000841.4

p.E568A

c.1703A>C

1 paper

NM_000841.4

p.D553Y

c.1657G>T

1 paper

NM_000841.4

p.P586A

c.1756C>G

1 paper

NM_000841.4

p.W587R

c.1759T>C

1 paper

NM_000841.4

p.W587R

c.1759T>A

1 paper

NM_000841.4

p.L594L

c.1782G>C

1 paper

NM_000841.4

p.T602M

c.1805C>T

1 paper

NM_000841.4

p.L522Q

c.1565T>A

1 paper

NM_000841.4

p.V628L

c.1882G>T

1 paper

NM_000841.4

p.V628L

c.1882G>C

1 paper

NM_000841.4

p.G660R

c.1978G>A