Varaico: Literature-Extracted Genetic Variants

GRM4

139 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 77–483UCSCReceptor family ligand binding region

NCD3Gaa 468–519UCSCNine Cysteines Domain of family 3 GPCR

NCD3Gaa 515–566UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 534–794UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 4

HGNC Alias Symbols

GPRC1D; mGlu4; MGLUR4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_000841.4

p.D485D

c.1455T>C

Surrounding Variants

1 paper

NM_000841.4

p.D485N

c.1453G>A

3 papers

NM_000841.4

p.S486F

c.1457C>T

1 paper

NM_000841.4

p.R483C

c.1447C>T

1 paper

NM_000841.4

p.L482P

c.1445T>C

2 papers

NM_000841.4

p.W495*

c.1484G>A

2 papers

NM_000841.4

p.W495*

c.1485G>A

1 paper

NM_000841.4

p.G469R

c.1405G>C

1 paper

NM_000841.4

p.G469R

c.1405G>A

1 paper

NM_000841.4

p.F465F

c.1395C>T

1 paper

NM_000841.4

p.G457Splc

c.1369+39C>T

1 paper

NM_000841.4

p.S456L

c.1367C>T

1 paper

NM_000841.4

p.P429H

c.1286C>A