Varaico: Literature-Extracted Genetic Variants

GRM4

139 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 77–483UCSCReceptor family ligand binding region

NCD3Gaa 468–519UCSCNine Cysteines Domain of family 3 GPCR

NCD3Gaa 515–566UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 534–794UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 4

HGNC Alias Symbols

GPRC1D; mGlu4; MGLUR4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000841.4

p.P320L

c.959C>T

Surrounding Variants

1 paper

NM_000841.4

p.K317R

c.950A>G

1 paper

NM_000841.4

p.S313G

c.937A>G

1 paper

NM_000841.4

p.A328T

c.982G>A

1 paper

NM_000841.4

p.D312A

c.935A>C

2 papers

NM_000841.4

p.S311A

c.931T>G

1 paper

NM_000841.4

p.V332I

c.994G>A

1 paper

NM_000841.4

p.F307L

c.921C>G

1 paper

NM_000841.4

p.F307L

c.921C>A

1 paper

NM_000841.4

p.F307L

c.919T>C

1 paper

NM_000841.4

p.F306Y

c.917T>A

1 paper

NM_000841.4

p.G304D

c.911G>A

1 paper

NM_000841.4

p.G304C

c.910G>T