Varaico: Literature-Extracted Genetic Variants

GRM4

139 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 77–483UCSCReceptor family ligand binding region

NCD3Gaa 468–519UCSCNine Cysteines Domain of family 3 GPCR

NCD3Gaa 515–566UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 534–794UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 4

HGNC Alias Symbols

GPRC1D; mGlu4; MGLUR4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000841.4

p.Q124R

c.371A>G

Surrounding Variants

1 paper

NM_000841.4

p.K129R

c.386A>G

1 paper

NM_000841.4

p.A115S

c.343G>T

1 paper

NM_000841.4

p.C109S

c.326G>C

1 paper

NM_000841.4

p.C109S

c.325T>A

1 paper

NM_000841.4

p.P141R

c.422C>G

1 paper

NM_000841.4

p.D107Y

c.319G>T

1 paper

NM_000841.4

p.R104S

c.310C>A

1 paper

NM_000841.4

p.R149H

c.446G>A

1 paper

NM_000841.4

p.V150M

c.448G>A

1 paper

NM_000841.4

p.N98I

c.293A>T

1 paper

NM_000841.4

p.V150V

c.450G>T

1 paper

NM_000841.4

p.P93L

c.278C>T