Varaico: Literature-Extracted Genetic Variants

GRM4

139 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 77–483UCSCReceptor family ligand binding region

NCD3Gaa 468–519UCSCNine Cysteines Domain of family 3 GPCR

NCD3Gaa 515–566UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 534–794UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 4

HGNC Alias Symbols

GPRC1D; mGlu4; MGLUR4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000841.4

p.K4N

c.12G>C

Surrounding Variants

1 paper

NM_000841.4

p.G6D

c.17G>A

1 paper

NM_000841.4

p.G8R

c.22G>C

1 paper

NM_000841.4

p.W9*

c.27G>A

1 paper

NM_000841.4

p.P15A

c.43C>G

1 paper

NM_000841.4

p.L19F

c.55C>T

1 paper

NM_000841.4

p.Y23Y

c.69C>T

1 paper

NM_000841.4

p.G24S

c.70G>A

1 paper

NM_000841.4

p.M27I

c.81G>A

1 paper

NM_000841.4

p.P34R

c.101C>G

2 papers

NM_000841.4

p.G53D

c.158G>A

1 paper

NM_000841.4

p.L54Q

c.161T>A

1 paper

NM_000841.4

p.H58Q

c.174T>A