Varaico: Literature-Extracted Genetic Variants

GRM5

270 papers

RefSeq Summary

This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 506–558UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 573–821UCSC7 transmembrane sweet-taste receptor of 3 GCPR

GluR_Homer-bdgaa 1162–1212UCSCHomer-binding domain of metabotropic glutamate receptor

Gene Aliases

HGNC Name

glutamate metabotropic receptor 5

HGNC Alias Symbols

MGLUR5; GPRC1E; mGlu5; PPP1R86

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001143831.3

p.S908R

c.2722A>C

Surrounding Variants

1 paper

NM_001143831.3

p.M907K

c.2720T>A

1 paper

NM_001143831.3

p.S908R

c.2724C>G

1 paper

NM_001143831.3

p.S908R

c.2724C>A

1 paper

NM_001143831.3

p.T906P

c.2716A>C

2 papers

NM_001143831.3

p.N901S

c.2702A>G

1 paper

NM_001143831.3

p.E891K

c.2671G>A