Varaico: Literature-Extracted Genetic Variants

GRM5

270 papers

RefSeq Summary

This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 506–558UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 573–821UCSC7 transmembrane sweet-taste receptor of 3 GCPR

GluR_Homer-bdgaa 1162–1212UCSCHomer-binding domain of metabotropic glutamate receptor

Gene Aliases

HGNC Name

glutamate metabotropic receptor 5

HGNC Alias Symbols

MGLUR5; GPRC1E; mGlu5; PPP1R86

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001143831.3

p.M1insFs

c.3dupG

Surrounding Variants

1 paper

NM_001143831.3

p.V2A

c.5T>C

1 paper

NM_001143831.3

p.V2L

c.4G>C

1 paper

NM_001143831.3

p.M1insFs

c.2dupT

1 paper

NM_001143831.3

p.M1V

c.1A>G

1 paper

NM_001143831.3

p.E14G

c.41A>G

1 paper

NM_001143831.3

p.S19N

c.56G>A

1 paper

NM_001143831.3

p.E24V

c.71A>T

1 paper

NM_001143831.3

p.A29A

c.87T>C

1 paper

NM_001143831.3

p.M31I

c.93G>T

1 paper

NM_001143831.3

p.M31I

c.93G>C

1 paper

NM_001143831.3

p.M31I

c.93G>A

1 paper

NM_001143831.3

p.P32L

c.95C>T