Varaico: Literature-Extracted Genetic Variants

GRM6

254 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–478UCSCReceptor family ligand binding region

NCD3Gaa 513–564UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 579–839UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 6

HGNC Alias Symbols

GPRC1F; mGlu6; MGLUR6; CSNB1B

Papers

RefSeq ID

Protein change

DNA change

1–12 of 279 variants

15 papers

NM_000843.4

p.R621*

c.1861C>T

11 papers

NM_000843.4

p.P46L

c.137C>T

10 papers

NM_000843.4

p.G58R

c.172G>C

10 papers

NM_000843.4

p.G58R

c.172G>A

10 papers

NM_000843.4

p.V243F

c.727G>T

10 papers

NM_000843.4

p.C522Y

c.1565G>A

9 papers

NM_000843.4

p.Q59P

c.176A>C

9 papers

NM_000843.4

p.G150S

c.448G>A

8 papers

NM_000843.4

p.G756D

c.2267G>A

8 papers

NM_000843.4

p.E781K

c.2341G>A

7 papers

NM_000843.4

p.V243fs

c.727_728fs

7 papers

NM_000843.4

p.G275D

c.824G>A