Varaico: Literature-Extracted Genetic Variants

GRM6

254 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–478UCSCReceptor family ligand binding region

NCD3Gaa 513–564UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 579–839UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 6

HGNC Alias Symbols

GPRC1F; mGlu6; MGLUR6; CSNB1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000843.4

p.V767delFs

c.2299delC

Surrounding Variants

1 paper

NM_000843.4

p.V767A

c.2300T>C

2 papers

NM_000843.4

p.V775M

c.2323G>A

8 papers

NM_000843.4

p.G756D

c.2267G>A

2 papers

NM_000843.4

p.N780N

c.2340C>T

8 papers

NM_000843.4

p.E781K

c.2341G>A

1 paper

NM_000843.4

p.S747S

c.2241G>A

1 paper

NM_000843.4

p.S747L

c.2240C>T

1 paper

NM_000843.4

p.V741V

c.2223G>A

1 paper

NM_000843.4

p.A738_G740delFs

c.2213_2219del7

1 paper

NM_000843.4

p.I794T

c.2381T>C

1 paper

NM_000843.4

p.V800M

c.2398G>A

3 papers

NM_000843.4

p.T732T

c.2196G>A