Varaico: Literature-Extracted Genetic Variants

GRM6

254 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–478UCSCReceptor family ligand binding region

NCD3Gaa 513–564UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 579–839UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 6

HGNC Alias Symbols

GPRC1F; mGlu6; MGLUR6; CSNB1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000843.4

p.A738_G740delFs

c.2213_2219del7

Surrounding Variants

1 paper

NM_000843.4

p.V741V

c.2223G>A

1 paper

NM_000843.4

p.S747L

c.2240C>T

1 paper

NM_000843.4

p.S747S

c.2241G>A

3 papers

NM_000843.4

p.T732T

c.2196G>A

1 paper

NM_000843.4

p.Y727_E728insG

c.2179_2183ins3

8 papers

NM_000843.4

p.G756D

c.2267G>A

1 paper

NM_000843.4

p.I725F

c.2173A>T

1 paper

NM_000843.4

p.S723G

c.2167A>G

1 paper

NM_000843.4

p.P720S

c.2158C>T

4 papers

NM_000843.4

p.P720_P721insG

c.2158_2162ins3

1 paper

NM_000843.4

p.R719G

c.2155C>G

1 paper

NM_000843.4

p.V767A

c.2300T>C