Varaico: Literature-Extracted Genetic Variants

GRM6

254 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–478UCSCReceptor family ligand binding region

NCD3Gaa 513–564UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 579–839UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 6

HGNC Alias Symbols

GPRC1F; mGlu6; MGLUR6; CSNB1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000843.4

p.V148I

c.442G>A

Surrounding Variants

1 paper

NM_000843.4

p.V146G

c.437T>G

9 papers

NM_000843.4

p.G150S

c.448G>A

1 paper

NM_000843.4

p.S152A

c.454T>G

1 paper

NM_000843.4

p.V149_A151del0

c.445_453del9

1 paper

NM_000843.4

p.E143G

c.428A>G

1 paper

NM_000843.4

p.A153V

c.458C>T

1 paper

NM_000843.4

p.P142S

c.424C>T

1 paper

NM_000843.4

p.P141T

c.421C>A

1 paper

NM_000843.4

p.S155C

c.464C>G

1 paper

NM_000843.4

p.S157A

c.469T>G

1 paper

NM_000843.4

p.R138C

c.412C>T

1 paper

NM_000843.4

p.M159_V160insTAA

c.475_479ins9