Varaico: Literature-Extracted Genetic Variants

GRM6

254 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–478UCSCReceptor family ligand binding region

NCD3Gaa 513–564UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 579–839UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 6

HGNC Alias Symbols

GPRC1F; mGlu6; MGLUR6; CSNB1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

9 papers

NM_000843.4

p.Q59P

c.176A>C

Surrounding Variants

1 paper

NM_000843.4

p.G58V

c.173G>T

10 papers

NM_000843.4

p.G58R

c.172G>C

10 papers

NM_000843.4

p.G58R

c.172G>A

1 paper

NM_000843.4

p.A53_G54ins1

c.159_160insTAA

1 paper

NM_000843.4

p.R50_Q64del15

c.148_191del45

1 paper

NM_000843.4

p.A52delFs

c.155delG

1 paper

NM_000843.4

p.A52T

c.154G>A

5 papers

NM_000843.4

p.G51V

c.152G>T

1 paper

NM_000843.4

p.L69L

c.205C>T

1 paper

NM_000843.4

p.P46P

c.138G>A

11 papers

NM_000843.4

p.P46L

c.137C>T

1 paper

NM_000843.4

p.Y74H

c.220T>C