Varaico: Literature-Extracted Genetic Variants

GRM6

254 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–478UCSCReceptor family ligand binding region

NCD3Gaa 513–564UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 579–839UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 6

HGNC Alias Symbols

GPRC1F; mGlu6; MGLUR6; CSNB1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000843.4

p.L39V

c.115C>G

Surrounding Variants

1 paper

NM_000843.4

p.L39P

c.116T>C

1 paper

NM_000843.4

p.G38D

c.113G>A

1 paper

NM_000843.4

p.R34L

c.101G>T

1 paper

NM_000843.4

p.V33A

c.98T>C

11 papers

NM_000843.4

p.P46L

c.137C>T

1 paper

NM_000843.4

p.P46P

c.138G>A

5 papers

NM_000843.4

p.G51V

c.152G>T

4 papers

NM_000843.4

p.L26fs

c.76_77fs

1 paper

NM_000843.4

p.G25insFs

c.75dupC

1 paper

NM_000843.4

p.A52T

c.154G>A

1 paper

NM_000843.4

p.A19_G25insFs

c.57_75dup19

1 paper

NM_000843.4

p.L11_G25del0

c.33_74del42