Varaico: Literature-Extracted Genetic Variants

GRM6

254 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–478UCSCReceptor family ligand binding region

NCD3Gaa 513–564UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 579–839UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 6

HGNC Alias Symbols

GPRC1F; mGlu6; MGLUR6; CSNB1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000843.4

p.L12H

c.35T>A

Surrounding Variants

1 paper

NM_000843.4

p.L12L

c.36C>T

1 paper

NM_000843.4

p.L11L

c.31C>T

1 paper

NM_000843.4

p.R8R

c.24G>A

1 paper

NM_000843.4

p.A7T

c.19G>A

1 paper

NM_000843.4

p.W20*

c.59G>A

1 paper

NM_000843.4

p.W20*

c.60G>A

1 paper

NM_000843.4

p.A2E

c.5C>A

1 paper

NM_000843.4

p.M1I

c.3G>T

1 paper

NM_000843.4

p.M1I

c.3G>A

2 papers

NM_000843.4

p.P17_A22del0

c.50_64del15

1 paper

NM_000843.4

p.M1insFs

c.1_2insG

1 paper

NM_000843.4

p.A24S

c.70G>T