Varaico: Literature-Extracted Genetic Variants

GRM7

192 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved i...

Pfam Domains

ANF_receptoraa 77–485UCSCReceptor family ligand binding region

NCD3Gaa 518–569UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 584–844UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 7

HGNC Alias Symbols

GLUR7; GPRC1G; mGlu7; MGLUR7; PPP1R87

Papers

RefSeq ID

Protein change

DNA change

1–12 of 183 variants

12 papers

NM_000844.4

p.I154T

c.461T>C

11 papers

NM_000844.4

p.R658W

c.1972C>T

10 papers

NM_000844.4

p.Y433F

c.1298A>T

10 papers

NM_000844.4

p.W586*

c.1757G>A

10 papers

NM_000844.4

p.W586*

c.1758G>A

10 papers

NM_000844.4

p.T675K

c.2024C>A

8 papers

NM_000844.4

p.R622Q

c.1865G>A

6 papers

NM_000844.4

p.R658Q

c.1973G>A

6 papers

NM_000844.4

p.E891K

c.2671G>A

5 papers

NM_000844.4

p.R659*

c.1975C>T

4 papers

NM_000844.4

p.G471R

c.1411G>A

4 papers

NM_000844.4

p.G471R

c.1411G>C