Varaico: Literature-Extracted Genetic Variants

GRM7

192 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved i...

Pfam Domains

ANF_receptoraa 77–485UCSCReceptor family ligand binding region

NCD3Gaa 518–569UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 584–844UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 7

HGNC Alias Symbols

GLUR7; GPRC1G; mGlu7; MGLUR7; PPP1R87

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000844.4

p.A81V

c.242C>T

Surrounding Variants

1 paper

NM_000844.4

p.L83_Q88del6

c.247_263del18

1 paper

NM_000844.4

p.H77Q

c.231C>A

1 paper

NM_000844.4

p.H77Q

c.231C>G

2 papers

NM_000844.4

p.I76I

c.228C>T

2 papers

NM_000844.4

p.N74K

c.222C>A

2 papers

NM_000844.4

p.N74K

c.222C>G

2 papers

NM_000844.4

p.N74N

c.222C>T

1 paper

NM_000844.4

p.S91G

c.271A>G

1 paper

NM_000844.4

p.D69N

c.205G>A

1 paper

NM_000844.4

p.P62L

c.185C>T

1 paper

NM_000844.4

p.G102G

c.306C>G

1 paper

NM_000844.4

p.A59D

c.176C>A