Varaico: Literature-Extracted Genetic Variants

GRM7

192 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved i...

Pfam Domains

ANF_receptoraa 77–485UCSCReceptor family ligand binding region

NCD3Gaa 518–569UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 584–844UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 7

HGNC Alias Symbols

GLUR7; GPRC1G; mGlu7; MGLUR7; PPP1R87

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

12 papers

NM_000844.4

p.I154T

c.461T>C

Surrounding Variants

1 paper

NM_000844.4

p.S157A

c.469T>G

1 paper

NM_000844.4

p.S157S

c.471G>A

1 paper

NM_000844.4

p.G158E

c.473G>A

1 paper

NM_000844.4

p.G158A

c.473G>C

1 paper

NM_000844.4

p.V150I

c.448G>A

1 paper

NM_000844.4

p.S160A

c.478T>G

1 paper

NM_000844.4

p.Q173_I174Splc

c.519+1G>A

1 paper

NM_000844.4

p.Q173_I174Splc

c.519+7A>G

1 paper

NM_000844.4

p.Q124H

c.372G>C

1 paper

NM_000844.4

p.Q124H

c.372G>T

1 paper

NM_000844.4

p.F122L

c.366C>A

1 paper

NM_000844.4

p.F122L

c.366C>G