Varaico: Literature-Extracted Genetic Variants

GRM7

192 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved i...

Pfam Domains

ANF_receptoraa 77–485UCSCReceptor family ligand binding region

NCD3Gaa 518–569UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 584–844UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 7

HGNC Alias Symbols

GLUR7; GPRC1G; mGlu7; MGLUR7; PPP1R87

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000844.4

p.A414T

c.1240G>A

Surrounding Variants

1 paper

NM_000844.4

p.D413N

c.1237G>A

1 paper

NM_000844.4

p.K407T

c.1220A>C

1 paper

NM_000844.4

p.H420Q

c.1260C>A

1 paper

NM_000844.4

p.H420Q

c.1260C>G

10 papers

NM_000844.4

p.Y433F

c.1298A>T

2 papers

NM_000844.4

p.E394K

c.1180G>A

1 paper

NM_000844.4

p.Q442*

c.1324C>T

1 paper

NM_000844.4

p.V455A

c.1364T>C

4 papers

NM_000844.4

p.G471R

c.1411G>A

4 papers

NM_000844.4

p.G471R

c.1411G>C

1 paper

NM_000844.4

p.G471A

c.1412G>C

1 paper

NM_000844.4

p.R476H

c.1427G>A