Varaico: Literature-Extracted Genetic Variants

GRM7

192 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved i...

Pfam Domains

ANF_receptoraa 77–485UCSCReceptor family ligand binding region

NCD3Gaa 518–569UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 584–844UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 7

HGNC Alias Symbols

GLUR7; GPRC1G; mGlu7; MGLUR7; PPP1R87

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

10 papers

NM_000844.4

p.W586*

c.1757G>A

Surrounding Variants

10 papers

NM_000844.4

p.W586*

c.1758G>A

1 paper

NM_000844.4

p.S588F

c.1763C>T

1 paper

NM_000844.4

p.L584L

c.1750C>T

1 paper

NM_000844.4

p.I579F

c.1735A>T

1 paper

NM_000844.4

p.P594S

c.1780C>T

1 paper

NM_000844.4

p.D578N

c.1732G>A

1 paper

NM_000844.4

p.T574T

c.1722C>T

1 paper

NM_000844.4

p.A598T

c.1792G>A

1 paper

NM_000844.4

p.C563Y

c.1688G>A

1 paper

NM_000844.4

p.T611I

c.1832C>T

1 paper

NM_000844.4

p.R614H

c.1841G>A

1 paper

NM_000844.4

p.M558T

c.1673T>C