Varaico: Literature-Extracted Genetic Variants

GRM7

192 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved i...

Pfam Domains

ANF_receptoraa 77–485UCSCReceptor family ligand binding region

NCD3Gaa 518–569UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 584–844UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 7

HGNC Alias Symbols

GLUR7; GPRC1G; mGlu7; MGLUR7; PPP1R87

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000844.4

p.L632F

c.1894C>T

Surrounding Variants

1 paper

NM_000844.4

p.R626G

c.1876C>G

8 papers

NM_000844.4

p.R622Q

c.1865G>A

2 papers

NM_000844.4

p.T618M

c.1853C>T

1 paper

NM_000844.4

p.R614H

c.1841G>A

1 paper

NM_000844.4

p.T611I

c.1832C>T

11 papers

NM_000844.4

p.R658W

c.1972C>T

6 papers

NM_000844.4

p.R658Q

c.1973G>A

5 papers

NM_000844.4

p.R659*

c.1975C>T

1 paper

NM_000844.4

p.L664V

c.1990T>G

1 paper

NM_000844.4

p.G665G

c.1995T>A

1 paper

NM_000844.4

p.A598T

c.1792G>A

1 paper

NM_000844.4

p.P594S

c.1780C>T