Varaico: Literature-Extracted Genetic Variants

GRM7

192 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved i...

Pfam Domains

ANF_receptoraa 77–485UCSCReceptor family ligand binding region

NCD3Gaa 518–569UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 584–844UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 7

HGNC Alias Symbols

GLUR7; GPRC1G; mGlu7; MGLUR7; PPP1R87

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_000844.4

p.R658Q

c.1973G>A

Surrounding Variants

11 papers

NM_000844.4

p.R658W

c.1972C>T

5 papers

NM_000844.4

p.R659*

c.1975C>T

1 paper

NM_000844.4

p.L664V

c.1990T>G

1 paper

NM_000844.4

p.G665G

c.1995T>A

1 paper

NM_000844.4

p.A671G

c.2012C>G

10 papers

NM_000844.4

p.T675K

c.2024C>A

1 paper

NM_000844.4

p.T677P

c.2029A>C

1 paper

NM_000844.4

p.R679Q

c.2036G>A

1 paper

NM_000844.4

p.R682H

c.2045G>A

1 paper

NM_000844.4

p.L632F

c.1894C>T

3 papers

NM_000844.4

p.K689delFs

c.2067delA

1 paper

NM_000844.4

p.K689fs

c.2065_2066fs