Varaico: Literature-Extracted Genetic Variants

GRM7

192 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved i...

Pfam Domains

ANF_receptoraa 77–485UCSCReceptor family ligand binding region

NCD3Gaa 518–569UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 584–844UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 7

HGNC Alias Symbols

GLUR7; GPRC1G; mGlu7; MGLUR7; PPP1R87

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000844.4

p.Y732Y

c.2196T>C

Surrounding Variants

1 paper

NM_000844.4

p.P740S

c.2218C>T

1 paper

NM_000844.4

p.I719V

c.2155A>G

1 paper

NM_000844.4

p.G716R

c.2146G>A

1 paper

NM_000844.4

p.G716R

c.2146G>C

1 paper

NM_000844.4

p.L715_G716del2

c.2143_2147del6

1 paper

NM_000844.4

p.A704G

c.2111C>G

1 paper

NM_000844.4

p.T700K

c.2099C>A

1 paper

NM_000844.4

p.K689fs

c.2065_2066fs

2 papers

NM_000844.4

p.K689fs

c.2065_2066fs

3 papers

NM_000844.4

p.K689delFs

c.2067delA

1 paper

NM_000844.4

p.R682H

c.2045G>A

1 paper

NM_000844.4

p.F784S

c.2351T>C