Varaico: Literature-Extracted Genetic Variants

GRM7

192 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved i...

Pfam Domains

ANF_receptoraa 77–485UCSCReceptor family ligand binding region

NCD3Gaa 518–569UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 584–844UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 7

HGNC Alias Symbols

GLUR7; GPRC1G; mGlu7; MGLUR7; PPP1R87

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000844.4

p.E786D

c.2358A>T

Surrounding Variants

1 paper

NM_000844.4

p.E786D

c.2358A>C

1 paper

NM_000844.4

p.F784S

c.2351T>C

1 paper

NM_000844.4

p.Y795C

c.2384A>G

1 paper

NM_000844.4

p.T796M

c.2387C>T

1 paper

NM_000844.4

p.T796T

c.2388G>A

1 paper

NM_000844.4

p.A803S

c.2407G>T

3 papers

NM_000844.4

p.I807fs

c.2419_2420fs

1 paper

NM_000844.4

p.I807insFs

c.2419_2420insT

2 papers

NM_000844.4

p.I807delFs

c.2420delT

1 paper

NM_000844.4

p.F809fs

c.2425_2426fs

1 paper

NM_000844.4

p.P740S

c.2218C>T

1 paper

NM_000844.4

p.K817_L818Splc

c.2451+49T>A