Varaico: Literature-Extracted Genetic Variants

GRM7

192 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved i...

Pfam Domains

ANF_receptoraa 77–485UCSCReceptor family ligand binding region

NCD3Gaa 518–569UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 584–844UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 7

HGNC Alias Symbols

GLUR7; GPRC1G; mGlu7; MGLUR7; PPP1R87

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_000844.4

p.E891K

c.2671G>A

Surrounding Variants

1 paper

NM_000844.4

p.A888V

c.2663C>T

1 paper

NM_000844.4

p.D897E

c.2691C>A

1 paper

NM_000844.4

p.D897E

c.2691C>G

1 paper

NM_000844.4

p.S900Splc

c.2698+15G>A

1 paper

NM_000844.4

p.M872V

c.2614A>G

1 paper

NM_000844.4

p.A870T

c.2608G>A

1 paper

NM_000844.4

p.R861Q

c.2582G>A

1 paper

NM_000844.4

p.T823S

c.2468C>G

1 paper

NM_000844.4

p.T823S

c.2467A>T

2 papers

NM_000844.4

p.Q821*

c.2461C>T

1 paper

NM_000844.4

p.K817_L818Splc

c.2452-123T>C