Varaico: Literature-Extracted Genetic Variants

GRM8

229 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 74–479UCSCReceptor family ligand binding region

NCD3Gaa 511–562UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 577–837UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 8

HGNC Alias Symbols

GLUR8; GPRC1H; mGlu8; MGLUR8

Papers

RefSeq ID

Protein change

DNA change

1–12 of 377 variants

4 papers

NM_000845.3

p.F362Y

c.1085T>A

4 papers

NM_000845.3

p.H720delFs

c.2158delG

4 papers

NM_000845.3

p.H720fs

c.2158_2159fs

3 papers

NM_000845.3

p.T97A

c.289A>G

3 papers

NM_000845.3

p.I290V

c.868A>G

3 papers

NM_000845.3

p.E508K

c.1522G>A

3 papers

NM_000845.3

p.H720insFs

c.2158dupC

2 papers

NM_000845.3

p.R41Q

c.122G>A

2 papers

NM_000845.3

p.L48*

c.143T>A

2 papers

NM_000845.3

p.G58R

c.172G>C

2 papers

NM_000845.3

p.G58R

c.172G>A

2 papers

NM_000845.3

p.I83V

c.247A>G