Varaico: Literature-Extracted Genetic Variants

GRM8

229 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 74–479UCSCReceptor family ligand binding region

NCD3Gaa 511–562UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 577–837UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 8

HGNC Alias Symbols

GLUR8; GPRC1H; mGlu8; MGLUR8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000845.3

p.T786P

c.2356A>C

Surrounding Variants

1 paper

NM_000845.3

p.I783T

c.2348T>C

1 paper

NM_000845.3

p.T789S

c.2365A>T

2 papers

NM_000845.3

p.T789A

c.2365A>G

1 paper

NM_000845.3

p.T789P

c.2365A>C

1 paper

NM_000845.3

p.T789S

c.2366C>G

1 paper

NM_000845.3

p.P782S

c.2344C>T

1 paper

NM_000845.3

p.E779_A780delFs

c.2335_2338del4

1 paper

NM_000845.3

p.A780S

c.2338G>T

1 paper

NM_000845.3

p.I792F

c.2374A>T

1 paper

NM_000845.3

p.I792V

c.2374A>G

1 paper

NM_000845.3

p.N778S

c.2333A>G

1 paper

NM_000845.3

p.F777C

c.2330T>G