Varaico: Literature-Extracted Genetic Variants

GRM8

229 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 74–479UCSCReceptor family ligand binding region

NCD3Gaa 511–562UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 577–837UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 8

HGNC Alias Symbols

GLUR8; GPRC1H; mGlu8; MGLUR8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000845.3

p.P774Q

c.2321C>A

Surrounding Variants

1 paper

NM_000845.3

p.P774delFs

c.2320_2321delGG

1 paper

NM_000845.3

p.E775K

c.2323G>A

1 paper

NM_000845.3

p.V773D

c.2318T>A

1 paper

NM_000845.3

p.G772A

c.2315G>C

1 paper

NM_000845.3

p.G772C

c.2314G>T

1 paper

NM_000845.3

p.F777C

c.2330T>G

1 paper

NM_000845.3

p.R771I

c.2312G>T

1 paper

NM_000845.3

p.N778S

c.2333A>G

1 paper

NM_000845.3

p.K769N

c.2307A>T

1 paper

NM_000845.3

p.K769N

c.2307A>C

1 paper

NM_000845.3

p.A780S

c.2338G>T

1 paper

NM_000845.3

p.I768N

c.2303T>A