Varaico: Literature-Extracted Genetic Variants

GRM8

229 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 74–479UCSCReceptor family ligand binding region

NCD3Gaa 511–562UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 577–837UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 8

HGNC Alias Symbols

GLUR8; GPRC1H; mGlu8; MGLUR8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000845.3

p.S704T

c.2110T>A

Surrounding Variants

1 paper

NM_000845.3

p.F700V

c.2098T>G

1 paper

NM_000845.3

p.T699A

c.2095A>G

2 papers

NM_000845.3

p.V697A

c.2090T>C

1 paper

NM_000845.3

p.Q695H

c.2085G>T

1 paper

NM_000845.3

p.Q695H

c.2085G>C

1 paper

NM_000845.3

p.Q695L

c.2084A>T

1 paper

NM_000845.3

p.Q695R

c.2084A>G

1 paper

NM_000845.3

p.Q695P

c.2084A>C

1 paper

NM_000845.3

p.Q695E

c.2083C>G

1 paper

NM_000845.3

p.Q695K

c.2083C>A

2 papers

NM_000845.3

p.S694A

c.2080T>G

2 papers

NM_000845.3

p.A693G

c.2078C>G