Varaico: Literature-Extracted Genetic Variants

GRM8

229 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 74–479UCSCReceptor family ligand binding region

NCD3Gaa 511–562UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 577–837UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 8

HGNC Alias Symbols

GLUR8; GPRC1H; mGlu8; MGLUR8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000845.3

p.R651*

c.1951C>T

Surrounding Variants

2 papers

NM_000845.3

p.S649F

c.1946C>T

1 paper

NM_000845.3

p.V653I

c.1957G>A

1 paper

NM_000845.3

p.S662G

c.1984A>G

1 paper

NM_000845.3

p.T668A

c.2002A>G

1 paper

NM_000845.3

p.Y633F

c.1898A>T

1 paper

NM_000845.3

p.T670A

c.2008A>G

1 paper

NM_000845.3

p.L631P

c.1892T>C

1 paper

NM_000845.3

p.F630delFs

c.1890delA

1 paper

NM_000845.3

p.I629S

c.1886T>G

2 papers

NM_000845.3

p.G628R

c.1882G>C

2 papers

NM_000845.3

p.G628R

c.1882G>A

1 paper

NM_000845.3

p.I676L

c.2026A>T