Varaico: Literature-Extracted Genetic Variants

GRM8

229 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 74–479UCSCReceptor family ligand binding region

NCD3Gaa 511–562UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 577–837UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 8

HGNC Alias Symbols

GLUR8; GPRC1H; mGlu8; MGLUR8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000845.3

p.R607delFs

c.1820delC

Surrounding Variants

1 paper

NM_000845.3

p.R607C

c.1819C>T

1 paper

NM_000845.3

p.Y608C

c.1823A>G

1 paper

NM_000845.3

p.F605C

c.1814T>G

1 paper

NM_000845.3

p.T611K

c.1832C>A

1 paper

NM_000845.3

p.V603L

c.1807G>T

1 paper

NM_000845.3

p.V603L

c.1807G>C

1 paper

NM_000845.3

p.P612H

c.1835C>A

1 paper

NM_000845.3

p.I602M

c.1806C>G

1 paper

NM_000845.3

p.V614L

c.1840G>T

1 paper

NM_000845.3

p.V614L

c.1840G>C

2 papers

NM_000845.3

p.V614M

c.1840G>A

1 paper

NM_000845.3

p.T599delFs

c.1797delG