Varaico: Literature-Extracted Genetic Variants

GRM8

229 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 74–479UCSCReceptor family ligand binding region

NCD3Gaa 511–562UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 577–837UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 8

HGNC Alias Symbols

GLUR8; GPRC1H; mGlu8; MGLUR8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000845.3

p.G543D

c.1628G>A

Surrounding Variants

1 paper

NM_000845.3

p.Q547Q

c.1641G>A

1 paper

NM_000845.3

p.V548G

c.1643T>G

1 paper

NM_000845.3

p.H537Q

c.1611C>G

1 paper

NM_000845.3

p.H537Q

c.1611C>A

1 paper

NM_000845.3

p.W536C

c.1608G>T

1 paper

NM_000845.3

p.W536C

c.1608G>C

1 paper

NM_000845.3

p.E550K

c.1648G>A

1 paper

NM_000845.3

p.C535Y

c.1604G>A

1 paper

NM_000845.3

p.C553R

c.1657T>C

1 paper

NM_000845.3

p.L555R

c.1664T>G

1 paper

NM_000845.3

p.G531fs

c.1591_1592fs

1 paper

NM_000845.3

p.C556*

c.1668C>A