Varaico: Literature-Extracted Genetic Variants

GRM8

229 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 74–479UCSCReceptor family ligand binding region

NCD3Gaa 511–562UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 577–837UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 8

HGNC Alias Symbols

GLUR8; GPRC1H; mGlu8; MGLUR8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000845.3

p.C520R

c.1558T>C

Surrounding Variants

1 paper

NM_000845.3

p.P519P

c.1557G>A

1 paper

NM_000845.3

p.P522T

c.1564C>A

1 paper

NM_000845.3

p.S514T

c.1540T>A

1 paper

NM_000845.3

p.A513V

c.1538C>T

1 paper

NM_000845.3

p.P512L

c.1535C>T

1 paper

NM_000845.3

p.P512A

c.1534C>G

1 paper

NM_000845.3

p.T528M

c.1583C>T

1 paper

NM_000845.3

p.T528K

c.1583C>A

1 paper

NM_000845.3

p.V529M

c.1585G>A

1 paper

NM_000845.3

p.G531fs

c.1591_1592fs

3 papers

NM_000845.3

p.E508K

c.1522G>A

1 paper

NM_000845.3

p.C535Y

c.1604G>A