Varaico: Literature-Extracted Genetic Variants

GRM8

229 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 74–479UCSCReceptor family ligand binding region

NCD3Gaa 511–562UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 577–837UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 8

HGNC Alias Symbols

GLUR8; GPRC1H; mGlu8; MGLUR8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000845.3

p.N378S

c.1133A>G

Surrounding Variants

1 paper

NM_000845.3

p.R377K

c.1130G>A

1 paper

NM_000845.3

p.R377G

c.1129A>G

1 paper

NM_000845.3

p.H374P

c.1121A>C

1 paper

NM_000845.3

p.K382N

c.1146G>T

1 paper

NM_000845.3

p.K382N

c.1146G>C

1 paper

NM_000845.3

p.G368D

c.1103G>A

1 paper

NM_000845.3

p.E365D

c.1095G>T

1 paper

NM_000845.3

p.E365D

c.1095G>C

4 papers

NM_000845.3

p.F362Y

c.1085T>A

1 paper

NM_000845.3

p.A360E

c.1079C>A

1 paper

NM_000845.3

p.R355I

c.1064G>T

1 paper

NM_000845.3

p.R354Q

c.1061G>A