Varaico: Literature-Extracted Genetic Variants

GRM8

229 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 74–479UCSCReceptor family ligand binding region

NCD3Gaa 511–562UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 577–837UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 8

HGNC Alias Symbols

GLUR8; GPRC1H; mGlu8; MGLUR8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000845.3

p.K296fs

c.886_887fs

Surrounding Variants

1 paper

NM_000845.3

p.K296insFs

c.888dupA

2 papers

NM_000845.3

p.K296delFs

c.888delT

1 paper

NM_000845.3

p.L297fs

c.889_890fs

1 paper

NM_000845.3

p.A293G

c.878C>G

3 papers

NM_000845.3

p.I290V

c.868A>G

1 paper

NM_000845.3

p.I306N

c.917T>A

1 paper

NM_000845.3

p.D309A

c.926A>C

1 paper

NM_000845.3

p.D309E

c.927T>G

1 paper

NM_000845.3

p.D309E

c.927T>A

1 paper

NM_000845.3

p.P317S

c.949C>T

1 paper

NM_000845.3

p.E326K

c.976G>A

1 paper

NM_000845.3

p.G327V

c.980G>T