Varaico: Literature-Extracted Genetic Variants

GRM8

229 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 74–479UCSCReceptor family ligand binding region

NCD3Gaa 511–562UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 577–837UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 8

HGNC Alias Symbols

GLUR8; GPRC1H; mGlu8; MGLUR8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000845.3

p.G149G

c.447C>T

Surrounding Variants

1 paper

NM_000845.3

p.V150I

c.448G>A

1 paper

NM_000845.3

p.S148P

c.442T>C

1 paper

NM_000845.3

p.D145N

c.433G>A

1 paper

NM_000845.3

p.S157A

c.469T>G

1 paper

NM_000845.3

p.V158M

c.472G>A

1 paper

NM_000845.3

p.I160I

c.480C>T

1 paper

NM_000845.3

p.M161T

c.482T>C

1 paper

NM_000845.3

p.S159_M161delFs

c.476_482del7

1 paper

NM_000845.3

p.N135D

c.403A>G

1 paper

NM_000845.3

p.A134T

c.400G>A

1 paper

NM_000845.3

p.A128P

c.382G>C

1 paper

NM_000845.3

p.A112G

c.335C>G