Varaico: Literature-Extracted Genetic Variants

GRM8

229 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 74–479UCSCReceptor family ligand binding region

NCD3Gaa 511–562UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 577–837UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 8

HGNC Alias Symbols

GLUR8; GPRC1H; mGlu8; MGLUR8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000845.3

p.R108_D109insFs

c.323_326dup4

Surrounding Variants

1 paper

NM_000845.3

p.D109V

c.326A>T

1 paper

NM_000845.3

p.D109fs

c.325_326fs

1 paper

NM_000845.3

p.A112T

c.334G>A

1 paper

NM_000845.3

p.A112G

c.335C>G

1 paper

NM_000845.3

p.S94_D104del11

c.280_311del33

1 paper

NM_000845.3

p.L103F

c.307C>T

1 paper

NM_000845.3

p.R101H

c.302G>A

1 paper

NM_000845.3

p.G99S

c.295G>A

3 papers

NM_000845.3

p.T97A

c.289A>G

1 paper

NM_000845.3

p.N95S

c.284A>G

1 paper

NM_000845.3

p.A128P

c.382G>C

1 paper

NM_000845.3

p.D91N

c.271G>A