Varaico: Literature-Extracted Genetic Variants

GRM8

229 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 74–479UCSCReceptor family ligand binding region

NCD3Gaa 511–562UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 577–837UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 8

HGNC Alias Symbols

GLUR8; GPRC1H; mGlu8; MGLUR8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000845.3

p.L67M

c.199C>A

Surrounding Variants

1 paper

NM_000845.3

p.L67R

c.200T>G

1 paper

NM_000845.3

p.G65delFs

c.194_195delCC

1 paper

NM_000845.3

p.C64W

c.192T>G

1 paper

NM_000845.3

p.C64F

c.191G>T

1 paper

NM_000845.3

p.V62delFs

c.184delC

1 paper

NM_000845.3

p.K71fs

c.211_212fs

1 paper

NM_000845.3

p.K71delFs

c.212_213delCT

1 paper

NM_000845.3

p.G61E

c.182G>A

1 paper

NM_000845.3

p.G58E

c.173G>A

2 papers

NM_000845.3

p.G58R

c.172G>C

2 papers

NM_000845.3

p.G58R

c.172G>A

1 paper

NM_000845.3

p.A56T

c.166G>A